Pesticides: water dispersible granules have a lot to do in the future

At the second workshop on processing technology and production equipment for environmentally-friendly pesticide preparations held recently, pesticide-dispersed granules became a hot topic for discussion among participating experts. Experts believe that water-dispersible granules will play a big role in the future of China's pesticide market in the context of environmentally-friendly products that will gradually assume the main role of pesticides.
Water-dispersible granules are a new type of pesticides developed in the 1980s. Because of their good safety, no organic solvents and no dust, the advantages of packaging, transportation, and convenience are rapidly developed. As an important development direction of new pesticides and environmental protection formulations, water dispersible granules have become the main pesticide formulations at home and abroad in recent years. Domestic enterprises are very enthusiastic in the development, registration and promotion of water dispersible granules.
According to Zhang Zongxi, a professor at the China Chemical Industry Research Institute, water-dispersible granules are granular formulations that can rapidly disintegrate and disperse into high-suspension solid-liquid dispersion systems after entering the water, and do not use organic solvents. Content of up to 50% to 90%, dispersion, suspension stability, the suspension rate of up to 90%, the particle size after dispersion of 8 to 10 microns, efficacy and commercial performance. Pesticide active ingredients are not easily soluble in water and organic solvents. Pesticides with a melting point greater than 70°C are suitable for processing into water-dispersible granules.
Despite the rapid development, due to the fact that the new pesticide formulations in China have been lagging behind developed countries by more than 10 years, there is still a large gap between the understanding of this formulation and developed countries, especially in formula research and production process development. There are many issues that need to be studied and explored in terms of equipment support, continuous production, process control, and dust control in the production process. At present, although many domestic products are branded with the name of water-dispersible granules, the quality of products is uneven and the processing technology is very different. In addition, the overall scale of production of pesticide dispersible granules in China is relatively small, the production process and equipment technologies are relatively backward, the research and production of supporting auxiliaries lags behind, and the product quality is unstable. The number of companies in the industry is estimated to be over 30, but the production capacity exceeds 1,000 tons. No more than 5 homes.
According to Professor Dai Quan of the Institute of Chemical Industry of Anhui Province, water dispersible granules are divided into wet process and dry process. As one of the core technologies in the production of dosage forms, the granulation process is divided into spray granulation, rotary granulation, fluidized bed granulation and extrusion granulation. From the analysis of processing advantages, extrusion granulation can be regarded as the most competitive production method of water dispersible granules in terms of output, energy consumption, environment, and product adaptability, but its degree of continuousness is still greatly improved. space.
Zhang Zongxi pointed out that the development of water dispersible granules should focus on several aspects such as process selection, auxiliaries selection and safety performance, product performance and efficacy, original drug quality and formulation adjustment, in order to speed up the formation of scientific and reasonable processing methods.
Among them, the selection of water dispersible granules processing technology should consider various factors such as product scale, investment amount, degree of continuousization, quality of original drug and source stability. Zhang Zongxi believes that both wet granulation and dry granulation have advantages and disadvantages, and they should be specifically treated when they are selected. In the selection of additives, there are many kinds of key additives such as wetting agents and dispersants used in water dispersible granules, and they are mostly organic macromolecules. When selecting, attention should be paid to the stability of product brands and supply, which occurs at the supplier. When you change, you must first verify the test reproduction. It is understood that the key auxiliaries used in the domestic water dispersible granules are currently monopolized by several large foreign companies, and only the specialized auxiliaries such as polymeric carboxylate dispersants have achieved localization.
Dai Quan pointed out that the processing technology of water dispersible granules must also follow the direction of pharmaceutical processing, because the most advanced processing technology in the pesticide field is often extended from the medical field. According to the positioning of its own products, enterprises can decide which process to use for production.
Zhang Huiming, general manager of the company (Nantong) Chemical Co., Ltd., made an analysis of the industrialization of pesticide dispersible granules. He believes that the production of pesticide water dispersible granules requires the formulation, process, and equipment to provide technical support. The formula is the core, the process is the key, and the equipment is the foundation. Pesticide water dispersible granules are currently at the critical moment of development. To speed up the upgrading of pesticide preparations, he proposed to strengthen policy guidance in order to gradually replace most of the WPs in the next 3 to 5 years, and to guide large-scale original drug companies and formulation processing. Enterprises through the product chain to establish long-term stable division of labor cooperation, through the formation of a large-scale industrialization advantages. In addition, we should establish a sound standardization system to improve the quality of water dispersible granules; attach importance to scientific research investment, form a complete industrial chain, encourage research on safety, environmental protection, and cleanliness of advanced production processes, actively develop specialized complete sets of equipment, and support functional assistance. The independent development and application of the agent.

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11000*2000*1380

2750

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1000-1800

11000*2000*1380

2950

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